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Two stage cellularization strategy for the fabrication of bioartificial hearts
Two stage cellularization strategy for the fabrication of bioartificial hearts
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机译:生物人工心脏制造的两阶段细胞化策略
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摘要
In some embodiments, the present disclosure pertains to a method of fabricating an artificial heart muscle (AHM) patch. In some embodiments, the method includes obtaining and/or isolating cells from a subject. In some embodiments, the cells are primary cardiac cells. In some embodiments, the method further includes forming a scaffold. In some embodiments, the method includes seeding the cells in the fibrin gel scaffold. In some embodiments, the method includes culturing the cells seeded in the fibrin gel scaffold under conditions appropriate for the formation of an artificial heart muscle (AHM) patch.
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