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Quantifying MGMT protein for optimal cancer therapy of glioblastoma
Quantifying MGMT protein for optimal cancer therapy of glioblastoma
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机译:定量MGMT蛋白可用于胶质母细胞瘤的最佳癌症治疗
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摘要
Methods are provided for treating a cancer patient suffering from a glioblastoma (GBM) by administering to the patient an effective amount of temozolomide, wherein a mass spectrometry analysis of a protein digest of a formalin-fixed tumor sample from the patient evidences an amount of a MGMT fragment peptide less than or substantially equal to 150 amol/μg.
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