首页>
外国专利>
Tissue-derived biomaterial composition and methods for ocular and other therapeutic applications
Tissue-derived biomaterial composition and methods for ocular and other therapeutic applications
展开▼
机译:用于眼和其他治疗应用的组织来源的生物材料组合物和方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present disclosure relates to a composition and methods for preparing a tissue-derived, dissolved extracellular matrix. In implementations, the extracellular matrix composition includes components native to the cornea including liquefied corneal tissue. The extracellular matrix composition can be prepared by dissolving extracted corneas in an aqueous solution of inorganic base. The resulting solution is then dialyzed to achieve a physiological pH. In some implementations, the extracellular matrix composition can be seeded and/or chemically cross-linked to form a gel matrix. The extracellular matrix and/or the gel matrix can be seeded with a desired cell type (e.g., endothelial cells, epithelial cells, stromal keratocytes, etc.) to stimulate cell proliferation and regeneration.
展开▼