首页> 外国专利> USE OF AMINE CARBOXYBORANES AS THERAPEUTIC DELIVERY OF CARBON MONOXIDE AND AS GENERAL DRUG DELIVERY SYSTEM IN THE PRESENCE OF REACTIVE OXYGEN SPECIES

USE OF AMINE CARBOXYBORANES AS THERAPEUTIC DELIVERY OF CARBON MONOXIDE AND AS GENERAL DRUG DELIVERY SYSTEM IN THE PRESENCE OF REACTIVE OXYGEN SPECIES

机译:在存在活性氧的情况下使用胺类碳硼烷作为一氧化碳的治疗性输送和一般药物输送系统

摘要

Disclosed is a method of delivering therapeutic carbon monoxide to the cells and tissues of a patient which comprises administering thereto a compound of the formula XBY1Y2C(O)V (I) or pharmaceutically acceptable salts thereof. In addition, disclosed is a method of delivering a drug to a diseased cell or tissue by administering a compound of formula I either wherein at least one of X is a drug containing an amino group or V is a drug containing an amino group or hydroxyl group less a hydrogen on the amino or hydroxyl group. Further disclosed are novel compounds of Formula I.
机译:公开了一种将治疗性一氧化碳递送至患者的细胞和组织的方法,其包括向其施用式XBY1Y2C(O)V(I)的化合物或其药学上可接受的盐。另外,公开了一种通过给药式I化合物将药物递送到患病细胞或组织的方法,其中X中的至少一个是含有氨基的药物或V是含有氨基或羟基的药物氨基或羟基上的氢少。进一步公开了式I的新化合物。

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