首页>
外国专利>
Magnetic probes for in vivo capture and detection of extracellular vesicles
Magnetic probes for in vivo capture and detection of extracellular vesicles
展开▼
机译:用于体内捕获和检测细胞外囊泡的磁性探针
展开▼
页面导航
摘要
著录项
相似文献
摘要
Body-mountable devices are provided to detect the presence or status of an analyte in subsurface vasculature of a body by detecting fluorescent reporters that are bound to instances of the analyte in the subsurface vasculature. Such devices further operate to exert an attractive magnetic force on magnetic nanoparticle-containing probes that are configured to bind to the analyte, thus concentrating the analyte proximate the devices by magnetically exerting attractive forces on such probes that are bound to instances of the analyte. The analyte can be an extracellular vesicle that is characteristic of a cancer, and a body-mountable device as described herein could be used to detect such extracellular vesicles in a portion of subsurface vasculature such that a presence or status of a tumor could be determined based on an amount, presence, or other detected property of the extracellular vesicle.
展开▼