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COMPOSITION, FOR PREVENTING OR TREATING DRY EYE SYNDROME, CONTAINING POLYETHYLENE GLYCOL AND FLAVONOID NANOCOMPOSITE AS ACTIVE INGREDIENT
COMPOSITION, FOR PREVENTING OR TREATING DRY EYE SYNDROME, CONTAINING POLYETHYLENE GLYCOL AND FLAVONOID NANOCOMPOSITE AS ACTIVE INGREDIENT
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机译:用于预防或治疗干眼症的成分,含有聚乙烯乙二醇和黄酮纳米复合物作为有效成分
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摘要
A composition for preventing or treating dry eye syndrome includes nanocomposite of a polyethylene glycol and a flavonoid as an active ingredient, and in the present invention, a catechin/PEG nanocomposite having increased catechin bioavailability is prepared by using catechins which are an antioxidant and polyethylene glycol which is a hydrophilic polymer used in a drug delivery system, and an increase in tear generation, stabilization of corneal epithelial cells, an increase in conjunctival goblet cells and enhanced anti-inflammatory effects accordance to a PEG dosage by the catechin/PEG nanocomposite are confirmed in a mouse model with dry eye syndrome.
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