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Benzimidazole compounds and use thereof for treating Alzheimer's Disease or Huntington's Disease

机译:苯并咪唑化合物及其在治疗阿尔茨海默氏病或​​亨廷顿氏病中的用途

摘要

Benzimidazole compounds of formula (I), shown below, are disclosed. The compounds are potent human glutaminyl cyclase inhibitors. Also disclosed is a pharmaceutical composition containing one of these compounds and a pharmaceutical acceptable carrier, as well as a method of treating Alzheimer's disease or Huntington's disease by administering to a subject in need thereof an effective amount of such a compound.; embedded image
机译:公开了如下所示的式(I)的苯并咪唑化合物。该化合物是有效的人谷氨酰胺环化酶抑制剂。还公开了包含这些化合物之一和药学上可接受的载体的药物组合物,以及通过向有需要的受试者施用有效量的此类化合物来治疗阿尔茨海默氏病或​​亨廷顿氏病的方法。 “嵌入式图像”

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