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Compositions and methods related to a type-II CRISPR-Cas system in Lactobacillus buchneri

机译：布氏乳杆菌的II型CRISPR-Cas系统的组成和方法

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摘要

The present invention is directed to methods and compositions for typing of Lactobacillus buchneri bacterial strains, detecting the presence of a L. buchneri in a sample, identifying a strain of L. buchneri having resistance to an invasive foreign genetic element, modifying the resistance of bacteria and archeae to an invasive foreign genetic element, and introducing nicks into or cleaving double stranded DNA for genome editing. 展开▼

机译：本发明涉及用于分类布氏乳酸杆菌细菌菌株的方法和组合物，以检测 L的存在。样品中的布氏杆菌，鉴定出 L菌株。布氏杆菌对入侵的外来遗传元件具有抗性，改变细菌和古细菌对入侵的外来遗传元件的抗性，并在双链DNA中引入或切割缺口以进行基因组编辑。 展开▼

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公开/公告号US10584358B2

专利类型

公开/公告日2020-03-10

原文格式PDF

申请/专利权人 NORTH CAROLINA STATE UNIVERSITY;
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申请/专利号US201415032985

发明设计人 RODOLPHE BARRANGOU;ALEXANDRA E. BRINER;
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申请日2014-10-29

分类号C12N15/11;C12N9/12;C12N15/90;C12N15/74;C12N9/22;A61K38;

国家 US

入库时间 2022-08-21 11:25:58

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3. COMPOSITIONS AND METHODS RELATED TO A TYPE-II CRISPR-CAS SYSTEM IN LACTOBACILLUS BUCHNERI [P] . 美国专利： US2020157576A1 . 2020-05-21

机译：与布氏乳杆菌II型CRISPR-CAS系统有关的组成和方法

4. COMPOSITIONS AND METHODS RELATED TO A TYPE-II CRISPR-CAS SYSTEM IN LACTOBACILLUS BUCHNERI [P] . 美国专利： US2016289700A1 . 2016-10-06

机译：与布氏乳杆菌II型CRISPR-CAS系统有关的组成和方法

5. COMPOSITIONS AND METHODS RELATED TO A TYPE-II CRISPR-CAS SYSTEM IN LACTOBACILLUS BUCHNERI [P] . 世界知识产权组织专利： WO2015066119A1 . 2015-05-07

机译：与布氏乳杆菌II型CRISPR-CAS系统有关的组成和方法

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