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METHODS FOR ACUTE AND LONG-TERM TREATMENT OF OPIOID AND OPIOID-LIKE DRUG ADDICTION
METHODS FOR ACUTE AND LONG-TERM TREATMENT OF OPIOID AND OPIOID-LIKE DRUG ADDICTION
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机译:阿片类药物和阿片样药物成瘾的急性和长期治疗方法
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摘要
This invention is directed to a method of treating opioid or opioid-like drug addiction, including acute and post-acute withdrawal symptoms, comprising treating an addicted patient with ibogaine, ibogaine derivative, or pharmaceutically acceptable salt or solvate thereof at a dosage that provides an average serum concentration of about 50 ng/mL to about 850 ng/mL under conditions where the QT interval prolongation does not exceed about 50 milliseconds.
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机译:本发明涉及治疗阿片样物质或类阿片样药物成瘾(包括急性和急性戒断症状)的方法,该方法包括用依博加因,依博加因衍生物或其药学上可接受的盐或溶剂化物治疗成瘾的患者,其剂量应为在QT间隔延长不超过约50毫秒的条件下,平均血清浓度约为50 ng / mL至850 ng / mL。
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