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Compositions and Methods for Treating Secondary Tuberculosis and Nontuberculosis Mycobacterium Infections
Compositions and Methods for Treating Secondary Tuberculosis and Nontuberculosis Mycobacterium Infections
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机译:治疗继发性结核和非结核分枝杆菌感染的组合物和方法
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摘要
Provided herein are fusion polypeptides comprising at least two Mycobacterial antigens, wherein one Mycobacterial antigen is a strong central memory T cell activator, and wherein one Mycobacterial antigen is a strong effector memory T cell activator. Also provided herein are methods of making and using such fusion polypeptides for the prevention or treatment of a secondary Mycobacterium tuberculosis infection as well as for the prevention or treatment of a nontuberculous Mycobacterium infection in a mammal.
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