SUSTAINED RELEASE SMALL MOLECULE DRUG FORMULATION

摘要

An injectable depot formulation includes a biocompatible polymer, an organic solvent combined with the biocompatible polymer to form a viscous gel, and a small molecule drug incorporated in the viscous gel such that the formulation exhibits an in vivo release profile having a C_max to C_min ratio of less than 200 and a lag time less than 0.2.