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A Companion Diagnostic Method For Use In The Treatment of Irritable Bowel Syndrome With Dietary Interventions or Faecal Microbiota Transplant
A Companion Diagnostic Method For Use In The Treatment of Irritable Bowel Syndrome With Dietary Interventions or Faecal Microbiota Transplant
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机译:通过饮食干预或粪便微生物群移植治疗肠易激综合征的伴发诊断方法
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摘要
The present invention provides a diagnostic method which may be used to determine the likelihood that a subject with Irritable Bowel Syndrome (IBS) will respond to treatment with an IBS intervention diet or faecal microbiota transplant (FMT). In particular, the method may be used to predict, or determine the likelihood of, a positive response of the subject with IBS to treatment with an IBS intervention diet or FMT, especially to determine the likelihood that the dietary intervention or FMT may have a positive (i.e. beneficial) effect on the subject's GI tract, specifically the GI tract microbiota, or other symptoms or complications of IBS (e.g. reducing severity thereof). The method of the present invention is based on analysing the abundance of certain bacteria in GI tract samples, e.g. by nucleic acid analysis.
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