WATER-SOLUBLE COMPOUNDS WITH AGGREGATION-INDUCED EMISSION CHARACTERISTICS

摘要

The present subject matter relates to water-soluble, fluorescent compounds that have aggregation-induced emission (AIE) characteristics and exhibit near infrared (NIR) absorption. The compounds can be utilized as plasma-membrane specific bio-probes in cell imaging through a wash-free and fast staining procedure. In addition, the compounds can efficiently generate reactive oxygen species (ROS) in vivo when irradiated with visible light. As such, the compounds can be effective in killing cancer cells through image-guided, photodynamic therapy (PDT) processes.