Methods for mitochondria and organelle genome editing

摘要

The present invention provides for a method for editing a genome of a mitochondria or organelle, the method comprising: introducing a DNA fixing template into a mitochondria or organelle comprising a target DNA in the genome of the mitochondria or organelle, such that the DNA fixing template replaces the target DNA, and optionally selecting or screening for a phenotype of an eukaryotic cell comprising the mitochondria or organelle, wherein the DNA fixing template causes the phenotype.