Engineered Bacterial Strain that Reduces Antibiotic-Resistant Enterococcus Colonization in the GI Tract

摘要

The present disclosure provides engineered modified strains of Enterococcus faecalis (EF) that is able to produce bacteriocin but is inefficient at establishing long-term colonization of the GI track in an animal. Compositions comprising the modified strain and methods of use are also disclosed.