首页> 外国专利> USING CANCER OR PRE-CANCER SUBJECT SEQUENCING DATA AND A DATABASE OF THERAPY BIOMARKER DISTRIBUTIONS TO DETERMINE NORMALIZED BIOMARKER SCORES AND GENERATE A GRAPHICAL USER INTERFACE

USING CANCER OR PRE-CANCER SUBJECT SEQUENCING DATA AND A DATABASE OF THERAPY BIOMARKER DISTRIBUTIONS TO DETERMINE NORMALIZED BIOMARKER SCORES AND GENERATE A GRAPHICAL USER INTERFACE

机译:使用癌症或癌症前受试者测序数据和治疗生物标志物分布的数据库来确定标准化的生物标志物得分并生成图形用户界面

摘要

Techniques for generating therapy biomarker scores and visualizing same. The techniques include determining, using a patient's sequence data and distributions of biomarker values across one or more reference populations, a first set of normalized scores for a first set of biomarkers associated with a first therapy, and a second set of normalized scores for a second set of biomarkers associated with a second therapy, generating a graphical user interface (GUI) including a first portion associated with the first therapy and having at least one visual characteristic determined based on a normalized score of the respective biomarker in the first set of normalized scores; and a second portion associated with a second therapy and having at least one visual characteristic determined based on a normalized score of the respective biomarker in the second set of normalized scores; and displaying the generated GUI.
机译:产生治疗生物标志物分数并使之可视化的技术。所述技术包括使用患者的序列数据和一个或多个参考人群中生物标志物值的分布,确定与第一疗法相关的第一组生物标志物的第一组标准化分数,以及第二组第二标志物的第二组标准化分数。与第二种疗法相关的一组生物标记,生成图形用户界面(GUI),该图形用户界面包括与第一种疗法相关的第一部分,并具有至少一个视觉特征,该视觉特征基于第一组标准化分数中相应生物标记的标准化分数确定;第二部分,其与第二种疗法相关联,并具有至少一个视觉特征,该视觉特征是基于第二组归一化分数中各个生物标记物的归一化分数确定的;并显示生成的GUI。

著录项

  • 公开/公告号US2020058377A1

    专利类型

  • 公开/公告日2020-02-20

    原文格式PDF

  • 申请/专利权人 BOSTONGENE CORPORATION;

    申请/专利号US201916662280

  • 申请日2019-10-24

  • 分类号G16B45;G16H10/20;G16H70/20;G16H20/40;G16H20/10;G16H50/50;G16H20;G06F17/18;G16B50;G16B40;G16B20;G16B5;G06F16/28;G16H50/70;G16H50/20;C12Q1/6886;G16H50/30;

  • 国家 US

  • 入库时间 2022-08-21 11:22:23

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号