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GENE DETECTION CHIP, DETECTION METHOD THEREOF, AND MICROFLUIDIC CONTROL CHIP SYSTEM
GENE DETECTION CHIP, DETECTION METHOD THEREOF, AND MICROFLUIDIC CONTROL CHIP SYSTEM
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机译:基因检测芯片,其检测方法和微流控芯片
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摘要
Disclosed are a gene detection chip, in which a gene detection channel is formed by an injection port, a microchannel, a reaction cell, and an exit port. The surface of the reaction cell has an aptamer, and the aptamer is modified with a fluorescent label. A detection method and a manufacturing method of the gene detection chip and a microfluidic control chip system are also disclosed. Upon a gene detection being performed, the fluorescent light of the fluorescent label is firstly quenched, and then a sample solution is introduced into the reaction cell through the injection port. If the sample solution has target gene, the target gene will hybridize and combine with the aptamer on the surface of the reaction cell, so as to recover the fluorescent light; if the sample solution does not have the target gene, the fluorescent light stays in the quenched state.
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