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Recombinant RNA-Dependent RNA Polymerase of RNA Viruses
Recombinant RNA-Dependent RNA Polymerase of RNA Viruses
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机译:重组RNA依赖性RNA聚合酶或RNA病毒
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摘要
The present disclosure provides nucleic acids, expression vectors, host cells for producing recombinant viral RNA-dependent RNA polymerase (RdRp) polypeptides of viruses such as Ebola virus. The present disclosure also provides methods and substrates for assaying activity of a RdRp polypeptide or a RdRp complex. Also provided herein are inhibitors of RdRp polypeptides of viruses such as Ebola virus for use in treating or preventing viral infection.
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