首页>
外国专利>
SYSTEM AND METHOD FOR DETERMINING GLYCAN TOPOLOGY USING TANDEM MASS SPECTRA
SYSTEM AND METHOD FOR DETERMINING GLYCAN TOPOLOGY USING TANDEM MASS SPECTRA
展开▼
机译:利用串联质谱确定糖类拓扑的系统和方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The method presented herein includes acquiring a mass spectrum of a molecule that includes mass spectrum peaks corresponding to a precursor ion and fragment ions. The method also includes identifying at least a portion of the fragment ions in the mass spectrum as corresponding to one or more monomer subunit ion of the precursor ion by appending one or more of the fragment ions to an inferable constituent to produce a topology building block. The topology building block is then stored in a candidate pool as corresponding to one or more of the monomer subunit ion if the combined mass of the inferable constituent and one or more of the fragment ions satisfy a first user-defined mass tolerance. One or more candidate topology of the precursor ion is then obtained by combining a plurality of the topology building blocks that satisfy a second user-defined mass tolerance for the precursor ion.
展开▼