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SYSTEM AND METHOD FOR COLOR DECONVOLUTION OF A SLIDE IMAGE TO ASSIST IN THE ANALYSIS OF TISSUE SPECIMEN
SYSTEM AND METHOD FOR COLOR DECONVOLUTION OF A SLIDE IMAGE TO ASSIST IN THE ANALYSIS OF TISSUE SPECIMEN
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机译:用于组织样本分析的幻灯片图像颜色反卷积的系统和方法
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摘要
A tissue analysis system and method for the spectral deconvolution of a RGB digital image obtained from a stained biological tissue sample, by estimating the stain component images that are obtained from a staining system configuration, where the reference stain vectors are assumed to be sampled from a known color distribution. The prior knowledge of stain variability of the staining system is adopted as initial reference stain vectors and statistical distribution of their variability. Based on the initial reference stain vectors distribution, the tissue analysis system determines both the reference stain vectors and stain component images of the input image. The image is then deconvoluted based on the reference stain vectors and stain component images.
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