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SYNTHETIC BIOLOGICAL CIRCUITS FOR THE DETECTION OF TARGET ANALYTES USING A GLUCOSE METER IN A CELL-FREE SYSTEM
SYNTHETIC BIOLOGICAL CIRCUITS FOR THE DETECTION OF TARGET ANALYTES USING A GLUCOSE METER IN A CELL-FREE SYSTEM
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机译:无细胞系统中用葡萄糖计检测目标分析物的合成生物学电路
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摘要
Described are methods for generating a reporter molecule in response to a target analyte in a cell-free system. A synthetic biological circuit is used to modify the level of the reporter molecule in response to the presence of the target analyte. The reporter molecule may be glucose or another molecule readily detected using a device such as glucose monitor or other portable sensor. Also provided are kits comprising a cell-free system with a synthetic biological circuit that generates or consumes a reporter molecule in response to a target analyte.
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