首页> 外国专利> ANTITHROMBOTIC COMPOSITION CONTAINING POLYGONUM CUSPIDATUM SIEB. ET ZUCC. AND CINNAMOMUM CASSIA BLUME

ANTITHROMBOTIC COMPOSITION CONTAINING POLYGONUM CUSPIDATUM SIEB. ET ZUCC. AND CINNAMOMUM CASSIA BLUME

机译：包含虎杖SIEB的抗微生物成分。 ET ZUCC。和肉桂卷

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摘要

The present invention relates to an antithrombotic composition including Polygonum cuspidatum Sieb. et Zucc. and Cinnamomum cassia Blume as active ingredients, and preferably includes an extract obtained by mixing Polygonum cuspidatum Sieb. et Zucc. and Cinnamomum cassia Blume in a weight ratio of 1:2-2:1 and extracting the mixture. The composition of the present invention is highly effective in antithrombotic effects, identified as a platelet aggregation inhibitory effect, a thrombosis inhibitory effect, a thrombosis-delaying effect, and the like, and thus can be used as an effective herbal-medicine-based agent for preventing or treating thrombosis, an antithrombotic health food, and the like.

机译：本发明涉及一种抗血栓形成组合物，其包含虎杖（Polygonum cuspidatum） Sieb。 et Zucc。和肉桂肉桂作为有效成分，并且优选包括通过混合虎杖 Sieb获得的提取物。 et Zucc。重量比为1：2-2：1的肉桂和肉桂。本发明的组合物在抗血栓形成作用方面非常有效，被鉴定为血小板凝集抑制作用，血栓形成抑制作用，血栓形成延迟作用等，因此可以用作有效的基于草药的药剂。用于预防或治疗血栓形成，抗血栓保健食品等。 展开▼

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公开/公告号US2020282000A1

专利类型

公开/公告日2020-09-10

原文格式PDF

申请/专利权人 NATIONAL INSTITUTE FOR KOREAN MEDICINE DEVELOPMENT;NOVMETAPHARMA CO. LTD.;
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申请/专利号US201816759554

发明设计人 HYO JUNG KIM;SUN GUN KIM;JAI HYUN SO;HWA DONG LEE;HYE RYUNG KANG;
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申请日2018-09-20

分类号A61K36/704;A61K36/54;A61K9;

国家 US

入库时间 2022-08-21 11:21:01

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1. 虎杖总蒽醌及虎杖总蒽醌的酸性成分的应用及制剂 [P] . 中国专利： CN1766034A . 2006-05-03

2. 肉桂酰胺、肉桂酰胺的制备方法及包含肉桂酰胺的药物组合物 [P] . 中国专利： CN1918139A . 2007-02-21

3. ANTITHROMBOTIC COMPOSITION CONTAINING POLYGONUM CUSPIDATUM SIEB. ET ZUCC. AND CINNAMOMUM CASSIA BLUME [P] . 欧洲知识产权局专利： EP3701961A1 . 2020-09-02

机译：包含虎杖SIEB的抗微生物成分。 ET ZUCC。和肉桂卷

4. ANTITHROMBOTIC COMPOSITION CONTAINING POLYGONUM CUSPIDATUM SIEB. ET ZUCC. AND CINNAMOMUM CASSIA BLUME [P] . 世界知识产权组织专利： WO2019083168A1 . 2019-05-02

机译：包含虎杖SIEB的抗微生物成分。 ET ZUCC。和肉桂卷

5. COMPOSITION COMPRISING EXTRACT OF POLYGONUM CUSPIDATUM SIEB. et ZUCC. AND CINNAMOMUM CASSIA BLUME FOR PREVENTING IMPROVING OR TREATING OF BONE LOSS RELATED DISEASE [P] . KR102302734B1 . 2021-09-15

机译：包含聚谷氨酸纤豆菌的提取物的组合物。等Zucc。和Cinnamomum cassia Blume用于预防改善或治疗骨质流失相关疾病

1. Optimization of extraction and determination of emodin from Polygonum cuspidatum Sieb. et Zucc. products by HPLC-DAD [J] . LU Hong-mei, LIANG Yi-zeng, NI Wang-dong, 中南大学学报（英文版） . 2006,第006期

2. DETERMINATION OF POLYDATIN IN POLYGONUM CUSPIDTUM SIEB. ET ZUCC. BY TLC-FLUORESCENCE SPECTROPHOTOMETRY [J] . 许昭, 唐玉海, 李健军, 药物分析学报：英文版 . 2004,第001期

3. A simple method for the isolation and purification of resveratrol from Polygonum cuspidatum [J] . Dong-Geng Wang, Wen-Ying Liu, Guang-Tong Chen 药物分析学报（英文） . 2013,第004期

4. Chemical variability of the invasive neophytes Polygonum cuspidatum Sieb. and Zucc. and Polygonum sachalinensis F. Schmidt ex Maxim [J] . Fan Peihong, Hay Anne-Emmanuelle, Marston Andrew, Biochemical Systematics and Ecology . 2009,第1期

5. The study of ultrasound-assisted extraction of flavonoids from Polygonum cuspidatum Sieb. et Zucc. [J] . Jia Weiwei, Chen Zhenbin, Zhao Yingyu, Journal of Materials Research . 2019,第19期

6. Cardioprotective effects of the total flavonoids of Polygonum cuspidatum Sieb. et Zucc. Root extract on experimental myocardial infarction in mice [J] . Hai-Rong Yu, Yu-Lian Jiang, Dan-Dan Dong, Tropical Journal of Pharmaceutical Research . 2019,第2期

7. Optimization of steam distillation for extracting cinnamomum cassia oil from cinnamomum cassia bark [C] . Jianlong Li, Fengrui Sun, Weiwen Wang, International Conference on Advances in Materials, Mechatronics and Civil Engineering . 2018

8. Role of belowground fungal mutualisms and nutrient cycling alteration in invasion success of Polygonum cuspidatum Sieb & Zucc. (Polygonaceae) in the eastern United States [D] . Addington, Gretchen Ann 2011

9. Anti-inflammatory Activity of the Invasive Neophyte Polygonum Cuspidatum Sieb. and Zucc. (Polygonaceae) and the Chemical Comparison of the Invasive and Native Varieties with regard to Resveratrol [O] . Peihong Fan, Tao Zhang, Kurt Hostettmann 2013

10. Cardioprotective effects of the total flavonoids of Polygonum cuspidatum Sieb. et Zucc. Root extract on experimental myocardial infarction in mice [O] . Hai-Rong Yu, Yu-Lian Jiang, Dan-Dan Dong, 2019

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2. The Apoptotic Effect of the Methanol Extract of iPolygonum cuspidatum/ithrough Up-Regulation Death Receptor 5 and CHOP in HSC-2 Human Oral Cancer Cells [J] . Hyun-Ju Yu ,Ji-Ae Shin ,Eun-Sun Choi . 癌症治疗（英文） . 2012,第1期

3. 转化蘡薁(Vitis thunbergii Sieb.et Zucc.)PGIP提高了烟草病原相关酶的活性 [C] . 刘艳红 ,王刚 ,高志红 . 第三届全国果树分子生物学学术研讨会 . 2011

4. 有杜松(Juniperus rigida Sieb.et Zucc)参加群落的群落特征、生长速率及其与生境关系的研究 [A] . 李荣 . 2013