An illustrative embodiment includes a host device configured to communicate over a network with a storage system comprising a plurality of storage devices. The host device comprises a set of input-output queues and a multi-path input-output driver configured to select input-output operations from the set of input-output queues for delivery to the storage system over the network. The multi-path input-output driver is further configured to determine fabric identifiers for respective ones of a plurality of paths from the host device to the storage system, and to select particular ones of the paths for delivery of the input-output operations to the storage system based at least in part on the fabric identifiers. The fabric identifiers may be determined for the respective paths, for example, based at least in part on responses to a predetermined command sent over the paths by the multi-path input-output driver.
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