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NEW THERAPEUTIC STRATEGIES AGAINST BLOOD CANCER

机译:针对血液癌症的新治疗策略

摘要

The present invention relates to the combination of at least one agent and a reduced calorie intake for use in the treatment of a blood cancer. In particular the agent is a CD20 inhibitor Bruton's tyrosine kinase inhibitor, a phosphoinositide 3-kinase inhibitor, a class I and/class II histone deacetylase inhibitor, a non-taxane replication inhibitor or a proteasome inhibitor. The combination is advantageous in that it sensitize cancer cells to said agent while it protects normal cells from toxicity induced by said agent.
机译:本发明涉及用于治疗血液癌症的至少一种试剂和减少的卡路里摄入的组合。特别地,该试剂是CD20抑制剂Bruton的酪氨酸激酶抑制剂,磷酸肌醇3-激酶抑制剂,I类和/或II类组蛋白脱乙酰酶抑制剂,非紫杉烷复制抑制剂或蛋白酶体抑制剂。该组合是有利的,因为它使癌细胞对所述试剂敏感,同时保护正常细胞免受所述试剂诱导的毒性。

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