PROCESS OF OBTAINING AN ANTIFUNGAL AGENT BASED ON PROPOLIS TO INHIBIT GROWTH OF THE FUNGI THIELAVIOPSIS PARADOXA

摘要

Process of obtaining an antifungal agent based on propolis to inhibit the growth of the fungus thielaviopsis paradoxa The present patent refers to the development of an antifungal agent comprised by the formulation of bioactive fractions based on propolis as a control agent of the paradoxical thielaviopsis fungus. the techniques of extraction by maceration, microwave and pressurized liquid using different temperatures (50, 65, 80 ºc), ratio (1:10 and 1:50) and ethanol / water (70%) as extractor solvent, were used and allowed to obtain fractions of propolis with antifungal action and high biological potential for the development of new bioproducts, and with a wide spectrum of application in agricultural, pharmacological formulations and in the cosmetics and food industry.