METHOD FOR CANCER TREATMENT USING A BCL-2 INHIBITOR ALONG WITH AN ALPHA-EMITERED RADIOIMUNOTHERAPEUTIC

摘要

the present invention relates to a method for treating an individual suffering from cancer, comprising administering to the individual (i) a bcl-2 inhibitor in conjunction with (ii) an alpha emitting isotope-labeled agent targeting cancer cells in the individual, wherein the amounts of the bcl-2 inhibitor and the labeled agent, when administered together, are therapeutically effective. this invention further provides a method for inducing the death of a cancer cell, comprising bringing the cell into contact with (i) a bcl-2 inhibitor together with (ii) an alpha-emitting isotope-labeled agent that targets the cancer cell, wherein the amounts of the bcl-2 inhibitor and the labeled agent, when simultaneously brought into contact with the cell, are effective in inducing cell death.