methods to assist in determining whether an imaging test should be performed on a human individual who has suffered or may have suffered a head injury with the use of early biomarkers

摘要

methods that assist in determining whether an image exam, such as magnetic resonance imaging (rmi) or computed tomography (tc), should be performed on a human individual who has suffered or may have suffered an injury are described in this document on the head with the use of an early biomarker, such as ubiquitin l1 carboxy-terminal hydrolase (uch-l1), glial fibrillar acid protein (gfap), or a combination thereof. these methods involve detecting levels and changes in uch-l1 levels in samples collected from a human individual at points in time within about 24 hours after the individual has suffered or may have suffered a head injury.