multiple epitope fusion protein, method for producing a composition, polynucleotide, recombinant vector, host cell, method for producing a multiple epitope fusion protein, immunodiagnostic test kit, composition, and, use of a multiple epitope fusion protein the present invention relates to compositions and methods for stimulating an immune response against esoterichia coli antigens producing shiga toxin (stec). the compositions include a multiple epitope fusion protein comprising more than one epitope of an immunogenic stec protein from more than one stec serotype. Additional compositions include at least two purified stec proteins, where the stec proteins are selected from a full-length stec protein, an immunogenic fragment or a variant thereof, where at least one of the stec proteins generates antibodies that react with stec 0157 and at least one other stec serotype.
展开▼