COMBINATION OF A MEK INHIBITOR COBIMETINIB AND AN ERK INHIBITOR (S)-1-(1-(4-CHLORO-3-FLUOROPHENYL)-2-HYDROXYETHYL)-4-(2-((1-METHYL-1H-PYRAZOL-5-YL)AMINO)PYRIMIDIN-4-YL)PYRIDIN-2(1H)-ONE FOR USE IN TREATMENT OF CANCER DISEASES

摘要

The invention provides a method of treatment, a kit and the use of a combination of a MEK inhibitor cobimetinib and an ERK inhibitor (S)-1-(1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one for the treatment or for the preparation of a medicament for the treatment of a hyperproliferative disorder, which is cancer.