SINGLE HIGH DOSES OF MVA INDUCE A PROTECTIVE IMMUNE RESPONSE IN NEONATES AND INFANTS

摘要

The present invention relates to compositions and methods for inducing a protective immune response against a poxvirus in human neonates or infants of less than 6 months of age. The present invention encompasses administering a single high dose of an MVA to a human neonate or infant of less than 6 months of age, wherein the administration induces protective T- and B-cell responses against a poxvirus in the human neonate or infant.