;or a pharmaceutically acceptable salt thereof. The invention also relates to a pharmaceutical composition for treating lung cancer, comprising a glutaminase inhibitor and erlotinib, wherein the glutaminase inhibitor is a compound of formula Ia. The invention provides the improved treatment of lung cancer."/> COMBINATION OF ERLOTINIB AND GLUTAMINASE INHIBITOR FOR TREATING LUNG CANCER
首页> 外国专利> COMBINATION OF ERLOTINIB AND GLUTAMINASE INHIBITOR FOR TREATING LUNG CANCER

COMBINATION OF ERLOTINIB AND GLUTAMINASE INHIBITOR FOR TREATING LUNG CANCER

机译:厄洛替尼联合谷氨酰胺酶抑制剂治疗肺癌

摘要

The invention relates to a method of treating or preventing cancer, comprising conjointly administering a glutaminase inhibitor and erlotinib, wherein cancer is lung cancer and the glutaminase inhibitor is a compound of formula Ia; ;or a pharmaceutically acceptable salt thereof. The invention also relates to a pharmaceutical composition for treating lung cancer, comprising a glutaminase inhibitor and erlotinib, wherein the glutaminase inhibitor is a compound of formula Ia. The invention provides the improved treatment of lung cancer.
机译:本发明涉及一种治疗或预​​防癌症的方法,包括联合给予谷氨酰胺酶抑制剂和厄洛替尼,其中癌症是肺癌,而谷氨酰胺酶抑制剂是式Ia的化合物。 <图像文件=“ IMGA0002.GIF” he =“ 24” imgContent =“绘图” imgFormat =“ GIF” wi =“ 70” /> ;或其药学上可接受的盐。本发明还涉及用于治疗肺癌的药物组合物,其包含谷氨酰胺酶抑制剂和厄洛替尼,其中所述谷氨酰胺酶抑制剂是式Ia的化合物。本发明提供了肺癌的改良治疗。

著录项

  • 公开/公告号EA036001B1

    专利类型

  • 公开/公告日2020-09-11

    原文格式PDF

  • 申请/专利权人 CALITHERA BIOSCIENCES INC.;

    申请/专利号EA20160092511

  • 申请日2015-06-12

  • 分类号A61K45/06;A61K31/501;A61K31/433;A61P35;A61P37;A61P25;

  • 国家 EA

  • 入库时间 2022-08-21 11:17:33

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