首页> 外国专利> A NEW METHOD OF IMMUNOTHERAPY OF SEVERAL KINDS OF TUMOR BLOOD DISEASES SUCH AS Acute Myeloid Leukemia (AML)

A NEW METHOD OF IMMUNOTHERAPY OF SEVERAL KINDS OF TUMOR BLOOD DISEASES SUCH AS Acute Myeloid Leukemia (AML)

机译:急性骨髓性白血病(AML)对多种血液系统疾病进行免疫治疗的新方法

摘要

The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to cancer immunotherapy. The present invention further relates to tumor-associated cytotoxic peptide T-cell epitopes (CTLs), alone or in combination with other tumor-associated peptides, which serve as active pharmaceutical ingredients in vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to several new peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells, which can be used in vaccine compositions for eliciting anti-tumor immune responses.
机译:本发明涉及用于免疫治疗方法的肽,核酸和细胞。特别地,本发明涉及癌症免疫疗法。本发明进一步涉及单独或与其他肿瘤相关肽组合的肿瘤相关细胞毒性肽T细胞表位(CTL),其在刺激抗肿瘤免疫应答的疫苗组合物中用作活性药物成分。本发明涉及源自人肿瘤细胞的HLA I类和HLA II类分子的几种新的肽序列及其变体,其可用于疫苗组合物中以引发抗肿瘤免疫应答。

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