Methods of generating pluripotent stem cell-derived retinal pigment epithelium cells

摘要

A method for promoting directed differentiation of human stem cells (hSCs) into retinal pigment epithelium (RPE) fate, the method comprising: a. providing a cell culture comprising hSCs; b. culturing cells in a culture system comprising a basic medium supplemented with one or more members of transforming growth factor ² (TGF ²) superfamily, whereby said hSCs are induced to differentiate into RPE fate.