Process for purification and separation of cannabinoids from dried hemp and cannabis leaves

摘要

Disclosed is a method for purification and separation of cannabinoids, specifically cannabidiol and tetrahydrocannabinol, from the dried hemp and cannabis leaves using a combination of a sequence of purification steps including: filtration, decolorization, activation or decarboxylation, dewaxing, a continuous simulated moving bed process, polishing, and crystallization to separate cannabinoids from tetrahydrocannabinol and to provide phytocannabinoid rich oil and cannabidiol isolate. The cannabinoid products can be used in various pharmaceutical and nutraceutical applications.