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Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent

机译:五价氮杂大环配合物和铂类抗癌药联合治疗癌症

摘要

A method of treating a cancer in a mammalian subject afflicted with the cancer, consisting essentially of administering to the subject a therapeutically effective amount of a platinum-based anticancer agent, and administering to the subject a therapeutically effective amount of a pentaaza macrocyclic ring complex corresponding to the Formula (I) below, prior to, concomitantly with, or after administration of the platinum-based anticancer agent, whereby response of the cancer to the platinum-based anticancer agent is increased.
机译:一种在患有癌症的哺乳动物受试者中治疗癌症的方法,该方法基本上包括:向受试者施用治疗有效量的铂基抗癌剂,以及向受试者施用治疗有效量的相应的五氮杂大环配合物在施用铂基抗癌剂之前,同时或之后,如果将其与以下式(I)的式(I)相比,则癌症对铂基抗癌剂的反应增加。

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