Large cycle compounds and their use

摘要

Refers to a large formulation compound (I),Rx2 and rx2 are independent,S. Among other things; R1 is h, deuterium, C1-C6 tar; each R2 and R3 is independent, h, deuterium, C1-C6 is tar, etc.; R4 is h, among others; R5 is h, or - nr6r7; each R6, R7 and R8 are selected from h, C2-C6, alquenilo, etc.; R9 is h, fluorine, chlorine, etc.; R10 is h, Fluorine, chlorine or bromine and N are 1 or 2. This compound inhibits SRC and met and / or csf1r belts and is effective in cancer treatment. It also refers to pharmacological composers containing this compound