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Method for enantio-selective running of the Diels-Alder reactions

机译:Diels-Alder反应的对映选择性运行的方法

摘要

The purpose of the notification is to identify the selective management of the Diels -Alder reaction between cyclopentadiene and crotonium aldehyde (but -2 -enal) in the ion fluid environment. This is characterised by the fact that the reaction takes place in the presence of a chiral complex made in situ of metal salt and a chiral ligand. The metal salt is dissolved in an ion liquid and then a ligand dissolved in anhydrous methylene chloride is introduced, after which both solutions are mixed for 24 -hour periods to obtain a chiral complex,the solution is then distilled under reduced pressure of methylene chloride and the crotonium aldehyde and cyclopentaden are added to the catalytic converter and the reaction is carried out at a temperature from 20oC to 25oC, over 4 -48 hours.
机译:该通知的目的是确定离子液体环境中环戊二烯与巴豆醛(但-2-烯醛)之间的Diels -Alder反应的选择性管理。其特征在于该反应在金属盐和手性配体的原位制备的手性络合物的存在下进行。将金属盐溶解在离子液体中,然后引入溶解在无水二氯甲烷中的配体,然后将两种溶液混合24小时,以获得手性络合物,然后在减压下将溶液蒸馏至二氯甲烷和将巴豆醛和环戊烯加到催化转化器中,反应在20℃至25℃的温度下进行4 -48小时。

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