Method of preparing pyrene derivatives of ferrocene carbaldehyde

摘要

The purpose of the notification is to obtain pyrethane derivatives of ferrocene carbonaldehyde with a generic formula 1 in which R stands for the NH or aromatic compound NH-C6H4-NH-CH2. Receiving a pyrethane derivative of ferrocene carbonaldehyde of the generic formula 1, where R stands for the -NH-,is that ferrocene carbaldehyde is reacted with 1-aminopyrene used in the quantity of 1,2 equivalent to ferrocene carbaldehyde in the presence of formic acid or acetic acid in methyl alcohol or ethyl alcohol and the name obtained is reduced by tetrahydroborate used in the quantitythese four equivalents to ferrocene carbohydride. The reaction product is separated by a silicon gel column chromatography using as an eluent a mixture of methylene-hexane chlorides in volume 2: 1Receiving a pyrene-derived ferrocene carbonide of a general formula 1where R stands for the aromatic compound NH-C6H4-NH-CH2,is that, in the first stage, ferrocene carbaldehyde undergoes a reaction with benzene-1,4-diamine used in the quantity of 5-equivalents to ferrocene carbaldehyde in methyl alcohol or methyl alcohol and the name obtained is reduced by tetrahydroborate used in the quantity of 8-equivalentsferrocene carbonaldehyde and N-(ferroceneylmethyl)benzene-1,4-diamine obtained are separated by a column chromatography on silicon gel using a mixture of ethyl hexane acetate in volume 3:1 as the eluent. The second stage of the reaction isthat pyrene 1-carbonaldehyde is reacted with N-(ferroceneylmethyl)benzene-1,4-diamine used in the quantity of 1,2-equivalent to pyrene 1-carbonaldehyde in the presence of formic acid or acetic acid in methyl alcohol or ethyl alcohol and the name obtained is reduced by sodium tetrahydroborate used in the quantity 4-equivalents to N-(ferroceneylmethyl)benzene-1,4-diamine, and the reaction product is separated by separation of the after-action mixture.