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A NON-INVASIVE METHOD FOR MONITORING TRANSPLANTED ORGAN STATUS IN ORGAN-TRANSPLANT RECIPIENTS
A NON-INVASIVE METHOD FOR MONITORING TRANSPLANTED ORGAN STATUS IN ORGAN-TRANSPLANT RECIPIENTS
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机译:一种用于监测器官移植受体中被移植器官状态的非侵入性方法
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摘要
The present invention pertains to a non-invasive method for monitoring transplanted organ status in organ-transplant recipients by determining the ratio of donor derived marker sequences to the marker sequences of the transplant recipient from circulating cell free DNA of the transplant recipients using digital droplet PCR. The invention also determined a normalized threshold value of the total circulating cell free nucleic acids healthy as well as in post-transplantation patients for assessing and monitoring transplanted organ status in organ-transplant recipients.
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