DIMS0-150 nucleotide for use in the treatment of chronic active ulcerative colitis

摘要

The present invention relates to methods of preventing or reducing the need of colectomy. In particular, the present invention relates a method for preventing colectomy, wherein an oligonucleotide containing at least one unmethylated CG dinucleotide is administered to a patient in need thereof, typically a patient suffering from ulcerative colitis (UC). Further, the present invention relates to pharmaceutical compositions comprising said oligonucleotide for the prevention or reduction of need of colectomy.