首页> 外国专利> Multifunctionalized polysaccharide compounds and their use to target the cation independent 6-phosphate mannose receptor

Multifunctionalized polysaccharide compounds and their use to target the cation independent 6-phosphate mannose receptor

机译:多功能多糖化合物及其靶向非阳离子依赖的6-磷酸甘露糖受体的用途

摘要

The subject matter of the present invention is a compound characterized in that it has the general formula (I): in which P1, X, n, A, L and L1 are as defined in Claim 1. The present invention also relates to a process for preparing said compounds (I) and to the use thereof for targeting the cation-independent mannose 6-phosphate receptor (CI-M6PR). The subject matter of the invention is also a conjugate of formula (III): in which P1, X, n, A, L and L'1 are as defined in Claim 6, and the use thereof: - in a method for therapeutic treatment of the human or animal body, in particular chosen from enzyme replacement therapy, photodynamic therapy or cancer treatment, and/or - in a method of diagnosis, in particular of diseases or of ailments associated with an increase or with a decrease in CI-M6PR expression.
机译:本发明的主题是特征在于其具有通式(I)的化合物:其中P1,X,n,A,L和L1如权利要求1所定义。本发明还涉及一种方法用于制备所述化合物(I)及其在靶向不依赖阳离子的甘露糖6-磷酸受体(CI-M6PR)中的用途。本发明的主题还是式(III)的缀合物:其中P1,X,n,A,L和L'1如权利要求6所定义,及其用途:-在治疗方法中或人体的动物,特别是选自酶替代疗法,光动力疗法或癌症治疗,和/或-在诊断方法中,尤其是与CI-M6PR升高或降低有关的疾病或疾病表达。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号