Antibacterial compositions comprising copper oxo-hydroxide nanoparticles and their preparation

摘要

An antibacterial composition for use in the treatment of wounds, wherein the composition comprises ligand-modified copper oxo-hydroxide nanoparticles and a pharmaceutically acceptable carrier, wherein the copper oxo-hydroxide nanoparticles have a structure in which the Oxo or hydroxy groups are substituted non-stoichiometrically by one or more ligands, wherein the one or more ligands comprise a carboxylic acid ligand or an ionized form thereof and copper is present in the pharmaceutical formulation as free copper ions (Cu2 +) .