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METHODS TO ASSESS THE LIKELIHOOD OF DYSPLASIA OR ESOPHAGEAL ADENOCARCINOMA

机译:评估发育异常或食管腺癌的可能性的方法

摘要

The invention relates to a method for aiding assessment of the likelihood of dysplasia or esophageal adenocarcinoma being present in a subject, the method comprising (a) providing an oesophagal sample from said subject (b) determining the methylation status of (i)SLC22A18, (ii)PIGR, (iii)GJA12 and (iv)RIN2 in said sample wherein if 2 or more of said genes are methylated then an increased likelihood of presence of dysplasia or esophageal is determined. The invention also relates to apparatus for same.
机译:本发明涉及一种用于评估受试者中存在不典型增生或食道腺癌的可能性的方法,该方法包括(a)提供来自所述受试者的食道样品(b)确定(i)SLC22A18的甲基化状态,( ii)PIGR,(iii)GJA12和(iv)RIN2,其中如果两个或多个所述基因被甲基化,则确定存在异型增生或食道的可能性增加。本发明还涉及用于其的设备。

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