首页> 外国专利> METHOD FOR ENHANCING GENERATION OF ANTIGEN-SPECIFIC CYTOTOXIC T LYMPHOCYTES (CTL) AND ANTIBODIES

METHOD FOR ENHANCING GENERATION OF ANTIGEN-SPECIFIC CYTOTOXIC T LYMPHOCYTES (CTL) AND ANTIBODIES

机译:增强抗原特异性细胞毒性T淋巴细胞(CTL)和抗体的产生的方法

摘要

Provided are a composition, food and drink that exert, through oral ingestion of a lactic acid bacterium, a culture product thereof, a processed product thereof or a composition comprising the same, an effect of enhancing an immune response to an antigen, said antigen being administered via another route such as subcutaneous injection. A composition for oral ingestion for enhancing the proliferation of cytotoxic T lymphocytes (CTL) specific to an antigen and the production of an antibody specific to the antigen, said composition comprising a lactic acid bacterium strain Lactococcus lactis subsp. lactis capable of enhancing the proliferation of CTL and the production of the antibody, a culture product thereof or a processed product thereof and being to be used together with the antigen in the form of a vaccine.
机译:提供通过口服摄取乳酸菌,其培养产物,其加工产物或包含该乳酸菌的组合物的组合物,食物和饮料,其具有增强对抗原的免疫应答的作用,所述抗原为通过另一种途径如皮下注射给药。一种用于口服摄取的组合物,用于增强对抗原特异的细胞毒性T淋巴细胞(CTL)的增殖和对抗原特异的抗体的产生,所述组合物包含乳酸菌乳酸乳球菌亚种。能够增强CTL的增殖和抗体,其培养产物或它们的加工产物的生产的乳酸菌,可以与抗原一起以疫苗的形式使用。

著录项

  • 公开/公告号CA3003240C

    专利类型

  • 公开/公告日2020-06-02

    原文格式PDF

  • 申请/专利权人 KIRIN COMPANY LIMITED;

    申请/专利号CA20163003240

  • 申请日2016-10-25

  • 分类号A61K35/747;A23L33/10;A61K39;A61K39/02;A61K39/12;A61K39/39;A61P31/04;A61P35;A61P37/04;A61P43;C12N1/20;

  • 国家 CA

  • 入库时间 2022-08-21 11:14:53

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