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3,5-SUBSTITUTED DERIVATIVES OF THIAZOLIDINE-2,4-DIONE HAVING ANTIMICROBIAL ACTIVITY

机译:具有抗微生物活性的噻唑烷-2,4-二酮的3,5-取代基衍生物

摘要

The invention relates to a new class of compounds characterized, in particular, by high antifungal activity, of general formula (I): formula (I) where X and R1-R3 have the values indicated in the description. The invention also relates to pharmaceutical compositions containing said compounds and to the use of the aforesaid compounds for the treatment and/or prophylaxis of various infectious diseases in a subject, in particular diseases caused by fungal infections, such as diseases caused by candida and filamentous pathogens.
机译:本发明涉及一类新的化合物,其特征在于通式(I)的高抗真菌活性:通式(I),其中X和R 1 -R 3 具有描述中指示的值。本发明还涉及含有所述化合物的药物组合物,以及上述化合物在治疗和/或预防受试者的各种传染病中的用途,特别是由真菌感染引起的疾病,例如由念珠菌和丝状病原体引起的疾病。 。

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