MAGNETIC NANOPARTICLE CONCENTRATION AND TEMPERATURE MEASUREMENT METHOD BASED ON PARAMAGNETIC SHIFT

摘要

A magnetic nanoparticle concentration and temperature measurement method based on a paramagnetic shift, wherein same involves measuring, by means of a nuclear magnetic resonance device, the concentration and temperature of magnetic nanoparticles by measuring a chemical shift of a liquid sample containing paramagnetic particles, thereby effectively realizing the measurement of the concentration and temperature with a high measurement precision. The paramagnetic nanoparticles are added to a nuclear magnetic resonance sample reagent, and the paramagnetic shift of the sample is obtained by means of nuclear magnetic resonance. A resonance frequency is acquired through the paramagnetic shift, a magnetic susceptibility is acquired according to the relationship between the resonance frequency and the magnetic susceptibility of magnetic nanoparticles, and concentration information and temperature information of the sample are further inversely solved according to the relationships between the magnetic susceptibility of the magnetic nanoparticles and the concentration, and between the magnetic susceptibility of the magnetic nanoparticles and the temperature. According to simulation data, concentration measurement and high-precision temperature measurement of a magnetic nanoparticle sample can be effectively realized on the basis of paramagnetic shift information.