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Nulceoside phosphoroamidate esters and derivatives thereof, use and synthesis thereof
Nulceoside phosphoroamidate esters and derivatives thereof, use and synthesis thereof
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机译:核苷磷酰胺酸酯及其衍生物,用途和合成方法
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摘要
Phosphoramidate esters and related nucleotide analogs useful in polynucleotide sequencing techniques, and synthetic methods for preparing those compounds, are disclosed. These compounds include nucleotide phosphoramidates analogs that are modified on the alpha-phosphate to enable attachment of a variety of application-specific substituents such as tether molecules.
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