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Concise synthesis of urea derivatives of amphotericin B
Concise synthesis of urea derivatives of amphotericin B
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机译:两性霉素B的脲衍生物的简便合成
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摘要
Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti -fungal activity. Certain of the derivatives are C16 urea derivatives and C16 carbamate derivatives of AmB. Also provided are methods of making the AmB derivatives.
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