1alpha,25-dihydroxy-24,24-difluoro-19-nor-vitamin D3 analogs and their pharmaceutical uses

摘要

Disclosed are la,25-dihydroxy-24,24-difluoro-2-methylene-19-nor- vitamin D analogs of formula I and their pharmaceutical uses. These new vitamin D analogs are 19-nor-vitamin D analogs having two fluorine atom substitutions at the 24 position (C-24) in the side chain and optionally having a 2-methylene substituent.