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1-tetrahydropyranylcarbonyl-2,3-dihydro-1H-indole compounds for treating cancer

机译:1-四氢吡喃基羰基-2,3-二氢-1H-吲哚化合物用于治疗癌症

摘要

The present invention relates to certain novel 2,3-dihydro-1H-indole compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, more particularly for the treatment of cancer selected from the group consisting of melanoma, acute myeloid leukemia, chronic lymphocytic leukemia, colorectal cancer, breast cancer, lung cancer, ovarian cancer, fallopian tube carcinoma, primary peritoneal carcinoma, cervical cancer, gastric cancer, liver cancer, pancreatic cancer, thyroid cancer, glioblastoma, non- Hodgkin´s lymphoma, and Hodgkin´s lymphoma.
机译:本发明涉及某些新颖的2,3-二氢-1H-吲哚化合物,包含所述化合物的药物组合物以及使用所述化合物治疗癌症的方法,更特别地用于治疗选自急性黑素瘤的癌症骨髓性白血病,慢性淋巴细胞性白血病,结肠直肠癌,乳腺癌,肺癌,卵巢癌,输卵管癌,原发性腹膜癌,宫颈癌,胃癌,肝癌,胰腺癌,甲状腺癌,成胶质细胞瘤,非霍奇金淋巴瘤和霍奇金淋巴瘤。

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